Imagine accelerating the discovery of new therapeutics through the development of AI models for mining drug-cell interactions at unprecedented resolution. Tahoe Therapeutics (formerly Vevo) new release may have redefined the race to map the human cellular landscape in cancer. In an unusual move, Tahoe Therapeutics has released “Tahoe 100M”, a massive open-source dataset encompassing 100 million single-cell data points and 60,000 experiments, mapping 1,100 drug treatments across 50 cancer types. Tahoe 100M brings a 50-fold increase in publicly available perturbational single-cell data, positioning itself in the world’s largest single cell repository. Tahoe 100M includes what researchers call “single cell transcriptomics…
In case you missed Wednesday’s NYT Mini, you can find the answers here: Wondering what button might make a “whoosh” sound? Not sure what a tiny cotton swab might be? Don’t worry, because I’m here to help you with some extra clues and the answers for today’s NYT Mini crossword.…
The IRS is rapidly getting much, much smaller.In February, the agency laid off roughly 7,000 probationary employees from its 90,000-person workforce as part of the Trump administration’s widespread effort to reduce the size of the federal government. Then, in early March, the Associated Press reported that the IRS was drafting…
This Side Hustle Spotlight Q&A features Michael Satterlee, 17, of Clifton Park, New York. Satterlee is a full-time high school student and the founder of Solefully, a six-figure business that designs and 3D prints unique accessories for Crocs. Responses have been edited for length and clarity.Image Credit: Courtesy of Solefully.…
Becoming an entrepreneur is one of the most exciting decisions you can make. But is it hard? Well, yes. It’s not a stroll in the park, but it’s also not impossible and can be incredibly amazing. Starting your own business is rewarding, challenging and everything in between. Here’s the honest…
This week, Mark Zuckerberg took the stand in an antitrust trial that could result in the breakup of Meta’s social networking empire. It might be years before the nearly 3 billion users of the company’s flagship app Facebook—known internally as the Blue app—learn the fate of the service they still…
In case you missed Tuesday’s NYT Mini, you can find the answers here: Wondering what flight option saves money at the expense of sleep? Not sure which fashion magazine has a palindromic name? Don’t worry, because I’m here to help you with some extra clues and the answers for today’s…
We day traders are an impatient lot. After all, most investors and fund managers would pump their fists in ecstasy if their stock gained 50% in a year. Day traders are accustomed to seeing stocks move 50% in minutes.The problem is that the impatience for action and results is fully…
It only takes one viral moment for a small business to see its brand skyrocket into the global spotlight. Whether it’s a TikTok video, a trending hashtag or a product spotlight in a renowned publication, going viral is both an exciting and challenging experience.But the reality is that businesses can…
For Lisa Schulner-Fine and Michael Fine, the journey to business ownership began more than a decade ago in New York — when their newborn son wouldn’t fall asleep.”I would be in his room in the dark in the middle of the night, holding him, and I would start daydreaming,” Lisa,…
Discord is facing a new lawsuit from the state of New Jersey, which claims that the chat app is engaged in “deceptive and unconscionable business practices” that put its younger users in danger.The lawsuit, filed on Thursday, comes after a multiyear investigation by the New Jersey Office of Attorney General.…
Looking for Monday’s Wordle hints, clues and answer? You can find them here: Today is kind of a big deal because the second season of Andor releases its first three episodes on Disney+. As someone who believes this is one of the greatest Star Wars stories of all time—and frankly…
As an entrepreneur, one of your most important responsibilities is building a workplace culture where your team can truly thrive. You’ve likely heard the saying “culture eats strategy for breakfast” — and it’s true. Even the most brilliant strategies will fall flat if your people don’t feel empowered to speak…
At my company, Jotform, our intern program is serious business.When a new class of interns signs on to work with us, their first week is spent in training, getting them up to speed on who we are, what we do and how we do it. Then, we team them up…
In the coming years, agents are widely expected to take over more and more chores on behalf of humans, including using computers and smartphones. For now, though, they’re too error prone to be much use.A new agent called S2, created by the startup Simular AI, combines frontier models with models…
Spotlight
Katie Drummond: Very exciting promise by Howard Lutnick. I can’t wait to…
In the 1998 movie The Wedding Singer, one of the characters Sammy…
As business owners and entrepreneurs, it’s important for us to understand the…
Let’s be real about to-do lists for a minute. Most of them…
